<span>Extraction of DNA is important because of many reasons. With the ability to remove DNA from an organism, scientists can observe, manipulate, and classify the DNA.
Scientists can identify genetic disorders or diseases from studying DNA.
Scientists can possibly find cures for these causes by manipulating or experimenting with this DNA.
Scientists can accurately sort organisms into classes because of DNA uniqueness. If we didn't have DNA extraction, it would be a lot harder to decide which organisms are different from each other.
Scientists can genetically engineer some organisms to produce beneficial things. A common example is that of insulin. Scientists can genetically engineer insulin production so that people with diabetes can live longer.</span>
Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Carbon shares 4 electrons to complete its valence shell
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