The population of African and Eurasian peoples in the Americas grew steadily, while the indigenous population plummeted. Eurasian diseases such as influenza, bubonic plague and pneumonic plagues, yellow fever, smallpox, and malaria devastated the Native Americans, who did not have immunity to them. Conflict and outright warfare with Western European newcomers and other American tribes further reduced populations and disrupted traditional societies. The extent and causes of the decline have long been a subject of academic debate, along with its characterization as a genocide.
So maybe C
Well it was called the New England Colonies so I guess you could say that