Question

Duchene muscular dystrophy, or DMD, is a recessive, x-linked disease. What would you expect to see in the offspring of a woman wh
o has DMD and a man who does not have the disease?

All of their sons and none of their daughters would have the disease.
None of their children would have the disease, but they would all be carriers.
All of their daughters and none of their sons would have the disease.
Their daughters would have the disease and their sons would be carriers.

Answer 1

It is expected to see in the offspring of a woman who has DMD and a man who does not have the disease that all of their sons and none of their daughters will have the disease

Option A.

Explanation:

Duchene muscular dystrophy, also known as DMD is a recessive, x-linked disease. It occurs when there is a mutation in the dystrophin gene. This mutation further affects the muscles of the body leading it to degenerate and ultimately death.

When a woman with DMD and a man without DMD have an offspring, their daughters and the sons will get the mutated gene signature from the mother as she is the carrier. But since the father has normal genes, the daughters will become the carriers and will not be afflicted by it. This is because the normal X chromosome from the father will be passed on to them. The sons on the other hand will have the disease as they will get one of their mother's X chromosome which would be carrying the mutated gene.