Well the deadliest disaster in US history was in 1900, from the tropical Galveston cyclone in texas, which caused 6,000-12,000 deaths and around $28,000,000 in damage. Only 6 years later, the second deadliest disaster was the 1906 San Francisco hurricane and fire which claimed over 3,000 deaths.
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Article V creates a two-stage process for amending the Constitution:proposal and ratification. An amendment can be proposed by two-thirds of both houses of Congress or... By two-thirds of state legislatures requesting Congress to call a national convention to propose amendments.