Yes, it is true that Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia.
Focal malformations of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are important causes of intractable childhood epilepsy.
Using targeted and exome sequencing on DNA from resected brain samples and non-brain samples from 53 patients with FCD or HME, we identified pathogenic germline and mosaic mutations in multiple PI3K/AKT pathway genes in 9 patients, and a likely pathogenic variant in 1 additional patient.
Our data confirm the association of DEPDC5 with sporadic FCD but also implicate this gene for the first time in HME. Our findings suggest that modulation of the mammalian target of rapamycin pathway may hold promise for malformation-associated epilepsy.
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<span>Extraction of DNA is important because of many reasons. With the ability to remove DNA from an organism, scientists can observe, manipulate, and classify the DNA.
Scientists can identify genetic disorders or diseases from studying DNA.
Scientists can possibly find cures for these causes by manipulating or experimenting with this DNA.
Scientists can accurately sort organisms into classes because of DNA uniqueness. If we didn't have DNA extraction, it would be a lot harder to decide which organisms are different from each other.
Scientists can genetically engineer some organisms to produce beneficial things. A common example is that of insulin. Scientists can genetically engineer insulin production so that people with diabetes can live longer.</span>

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How the Scientific Method Works
BY WILLIAM HARRIS
Pasteur's Experiment
The steps of Pasteur's experiment are outlined below:
First, Pasteur prepared a nutrient broth similar to the broth one would use in soup.
Answer:
Factor Analysis
Explanation:
Factor Analysis is a statistical procedure that can be used to identify clusters of behaviors (such as verbal skills, intelligence) that are related to a trait.
Factor analysis helps to accumulate a lot of data in many variables into a few variables which can be used for further analysis or study. The aim of factor analysis is to aggregate individual behaviors into a minimized number of factors.
