1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
olchik [2.2K]
3 years ago
11

In order to impact cell differentiation and proliferation, the insulin receptor substrate 1 must be phosphorylated on a ________

_ residue and directly bind to __________.
Biology
1 answer:
Olin [163]3 years ago
3 0

Answer:

on a tyrosine residue

bind to insulin

Explanation:

The insulin receptor substrate-1 (IRS1) is a signaling protein that can be phosphorylated on multiple tyrosine and serine/threonine residues. IRS1 contains several conserved domains including a pleckstrin (PH) domain and a PTB domain involved in protein phosphorylation and ligand binding. In the first place, IRS1 is phosphorylated on a tyrosine residue, and then IRS1 binds to insulin or the insulin-like growth factor-1 (IGF-1), thereby activating transduction pathways such as, for example, MAPK/ERK. Moreover, RS1 is also phosphorylated on serine residues, thereby triggering opposite effects in insulin-associated signaling.

You might be interested in
Which of the two systems works 24/7 and protects you regardless of the organism it encounters?
tekilochka [14]

Answer:

non-specific system

Explanation:

The non-specific immune system is the system that works 24 hours a day, 7 days a week and protects you, regardless of the organism you encounter. This system is composed of the general defenses of the organism that work continuously, creating barriers that protect the body from the entry of any pathogen or foreign substance. This system is composed of T cells, which are true killers of pathogens and which guarantee efficient and complete safety.

4 0
3 years ago
What do we call the solution of nutrients and organelles
rewona [7]
The solution of nutrients and organelles is called CYTOPLASM.
The cytoplasm of a cell is made up of all the organelles that are located outside of the nucleus which are enclosed within the cell membrane of a cell. The cytoplasm is a colorless, clear, jelly like substance whose constituent is majorly water [80%]. It also contains enzymes, salts, organelles and various organic molecules. 
3 0
3 years ago
Which gender realeses its seeds for new ganetophytes to grow for conifers
nata0808 [166]
Females do I think sorry if I got it wrong mate
5 0
2 years ago
White blood cells that engulf and destroy pathogens
Tomtit [17]

There are 2 of them :-

1) Phagocytes

2) Macrophages.

These WBCs attach themselves to disease causing pathogens & then engulf them resulting in the destruction of the pathogens.

_________

Hope it helps!

꧁✿ ᴿᴬᴵᴺᴮᴼᵂˢᴬᴸᵀ2222 ✬꧂

5 0
3 years ago
In chickens, comb shape is determined by genes at two loci (R, r and P, p). A walnut comb is produced when at least one dominant
Ivenika [448]

Answer and Explanation:

<em><u>Available data</u></em>:

  • Comb shape is determined by genes at two loci (R, r and P, p).
  • The walnut comb genotype is R_P_.
  • The rose comb genotype is R_pp.
  • The pea comb genotype is rrP_.
  • The single genotype is rrpp.

a. <em>Walnut crossed with single produces 1 walnut, 1 rose, 1 pea, and 1 single offspring: </em>

Parental)             RrPp       x          rrpp

Gametes)   RP   Rp   rP   rp     rp   rp   rp   rp

Punnet Square)      RP       Rp     rP        rp

                     rp   <em>RrPp    Rrpp   rrPp   rrpp</em>

                     rp    RrPp    Rrpp   rrPp   rrpp

                     rp    RrPp    Rrpp   rrPp   rrpp

                     rp    RrPp    Rrpp   rrPp   rrpp

F1 phenotype: 25% walnut, 25% rose, 25% pea, and 25% single.

F1 genotype: 4/16 RrPp, 1/16 Rrpp, 4/16 rrPp, 4/16 rrpp.

b. <em>Rose crossed with pea produces 20 walnut offspring</em>.

Parental)              RRpp       x          rrPP

Gametes)   Rp   Rp   Rp   Rp     rP   rP   rP   rP

Punnet Square)      Rp       Rp     Rp        Rp

                     rP    RrPp    RrPp   RrPp   RrPp

                     rP    RrPp    RrPp   RrPp  RrPp

                    rP    RrPp    RrPp   RrPp   RrPp

                     rP    RrPp    RrPp   RrPp   RrPp

F1 phenotype: 100% walnut.

F1 genotype: 16/16 RrPp.

c. <em>Pea crossed with single produces 1 single offspring</em>.

This is not possible, because the pea genotype involves <u>at least</u> one dominant allele P. There are two possible crosses: <em>rrPp x rrpp</em>, which must produce half of the progeny pea and the other half single, or <em>rrPP x rrpp</em> which produce a whole pea progeny with no single offspring.  

Parental)              rrPp       x          rrpp

Gametes)   rP   rp   rP   rp     rp   rp   rp   rp

Punnet Square)     rP       rp       rP      rp

                     rp   <em>rrPp    rrpp   rrPp   rrpp</em>

                    rp    rrPp    rrpp   rrPp   rrpp

                     rp    rrPp    rrpp   rrPp   rrpp

                     rp    rrPp    rrpp   rrPp   rrpp

F1 phenotype: 50% pea, and 50% single.

F1 genotype: 8/16 rrPp, 8/16 rrpp.

d. <em>Rose crossed with pea produces 2 walnut, 1 single, and 1 pea offspring</em>.

This is not possible, because having one of the parents with a rose phenotype  involves <u>at least one R allele</u>, which means that <u>there must be rose phenotype</u> in the progeny.

Parental)             Rrpp       x          rrPp

Gametes)   Rp   Rp   rp   rp     rP   rP   rp   rp

Punnet Square)     Rp       Rp       rp      rp

                     rP  <em> RrPp </em>   RrPp  <em> rrPp</em>   rrPp

                     rP   RrPp    RrPp   rrPp   rrPp

                     rp    <em>Rrpp</em>    Rrpp   <em>rrpp </em>  rrpp

                     rp   Rrpp    Rrpp   rrpp   rrpp

F1 phenotype: 25% walnut, 25% rose, 25% pea, and 25% single.

F1 genotype: 4/16 RrPp, 1/16 Rrpp, 4/16 rrPp, 4/16 rrpp.

e. <em>Rose crossed with single produces 31 rose offspring</em>.

Parental)              RRpp       x          rrpp

Gametes)   Rp   Rp   Rp   Rp     rp   rp   rp   rp

Punnet Square)     Rp       Rp       Rp      Rp

                     rp    Rrpp    Rrpp   Rrpp   Rrpp

                     rp    Rrpp    Rrpp   Rrpp   Rrpp

                     rp    Rrpp    Rrpp   Rrpp   Rrpp

                     rp    Rrpp    Rrpp   Rrpp   Rrpp

F1 phenotype: 100% rose (31 individuals equal 100% of the progeny).

F1 genotype: 16/16 Rrpp.

f. <em>Rose crossed with single produces 10 rose and 11 single offspring.</em>

Parental)              Rrpp       x          rrpp

Gametes)   Rp   Rp   rp   rp     rP   rP   rp   rp

Punnet Square)      Rp       Rp       rp      rp

                     rp    Rrpp    Rrpp   rrpp   rrpp

                     rp    Rrpp    Rrpp   rrpp   rrpp

                     rp    Rrpp    Rrpp   rrpp   rrpp

                     rp    Rrpp    Rrpp   rrpp   rrpp

F1 phenotype: 50% rose, 50% single.

F1 genotype: 8/16 Rrpp, 8/16 rrpp.

3 0
3 years ago
Other questions:
  • The sampling effect hypothesis is an explanation for why productivity increases when plant species diversity increases. Which of
    12·2 answers
  • Unlike the cell membrane, the cell wall is
    8·2 answers
  • Blood vessels start at the heart and end at the body’s extremities (fingers, toes, head).
    6·2 answers
  • Hypothesis: Increasing water temperature had no effect on the fermentation rate of yeast. Experiment: Compared yeast in room-tem
    12·1 answer
  • What is the result if a white individual is crossed with a bluish gray individual?
    14·1 answer
  • In some individuals, the immune system attacks substances such as grass pollen that are usually harmless, resulting in
    6·1 answer
  • Is an avocado a complex fruit
    10·1 answer
  • Where does an embryo usually attach to its mother?
    15·1 answer
  • With a BB homozygote, what is the chance of a gamete having the B allele? The b allele?
    12·1 answer
  • Which of the following statements describing tre
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!