We quantified the number of neurons, senile plaques, and neurofibrillary tangles in a high-order association cortex to evaluate the link between dementia, neuronal loss, and neuropathological findings in Alzheimer's disease (AD). Using statistically unbiased, stereological counting techniques, we examined the superior temporal sulcus in 34 AD patients and 17 non-demented control volunteers. In non-demented control patients, the quantity of superior temporal sulcus neurons remained constant from the sixth to the ninth decade. More than half of the neurons in AD were gone. Both neuronal loss and neurofibrillary tangles grew in tandem with the length and severity of the illness, although neuronal loss outweighed neurofibrillary tangle accumulation by a factor of many.
<h3>What is Neurofibrillary ?</h3>
Inside the brain's cells are twisted fibers that are intractable, called neurofibrillary tangles. Most of the tau protein, which is a component of the microtubule structure, makes up these tangles. From one area of the nerve cell to another, the microtubule facilitates the movement of nutrients and other vital molecules.
These tangles interfere with the transport mechanism of the cell, impairing synaptic transmission between neurons. New research reveals that aberrant tau and beta-amyloid proteins, along with a number of other factors, may play a complex role in the development of the brain abnormalities associated with Alzheimer's disease.
A decrease in concentration and function of acetylcholine (ACh), a neurotransmitter crucial for processing memory and learning, is observed in Alzheimer's disease patients.
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The number of electrons in the outermost shell determines essentially the type of chemical reactions that an atom participates in it is because these electrons are involved in chemical reactions as they can be donated, shared and thus rearranged by forming covalent bonds to produce new substances
When plants and animals die, they become food for decomposers like bacteria, fungi and earthworms. Decomposers or saprotrophs recycle dead plants and animals into chemical nutrients like carbon and nitrogen that are released back into the soil, air and water.
The sugar pill serves as a control.
The control in experiments is a sample that remains the same throughout the experiment and it is used to compare the results of the main experiment to. It serves to guarantee that changes noted in the experiment are from the variables introduced and not something else.
The platypus , brown bear , lion and house cat are related cause they are all mammals , but the lion and house are the same family .. hope this helps :)
