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Sveta_85 [38]
3 years ago
13

One human disease is caused by a change in one codon in a gene from GAA to GUA. This disease is the result of..?

Biology
2 answers:
Ahat [919]3 years ago
7 0
<span>The answer is: a mutation. The mutation is the alteration of a nucleotide sequence in DNA. There are different types of mutations. If one or more nucleotides are substituted by one or more nucleotides, it is an example of substitution. In this example, GAA is changed to GUA as the result of a substitution of the second nucleotide A by U.Hope I helped! :) Cheers!</span>
uranmaximum [27]3 years ago
4 0
<span>If one human disease is caused by a change in one codon in a gene from GAA to GUA, then this disease is the result of a mutation. Genes have mutated in such a way that only one codon in a gene is changed, so as to give rise to a certain disease in a human being. Crossing-over, meiosis error, and polypoloidy cannot produce such mistakes. </span>
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grandfather of s.r is affected (xₐy) and grandmother is normal (xx) will produce

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 s.r's mother who is a carrier (xₐx) [as xₐy and xx will produce 100% carrier xₐx daughter]

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s.r's mother is a carrier (xₐx) but her father is normal (xy) will produce,

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s.r who has 50% chance of being carrier (xₐx) and 50% chance of being normal (xx) [as she is the only child] and she has a normal (xy) partner, they will give,

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  1. if s.r is a carrier (xₐx) then one of her son will be affected (xₐy)   [as xₐx and xy =xₐy]
  2. if s.r is normal (xx) then her son will be normal (xy) [as xx and xy will give xy]

here,<u> 50% chance of her son to be affected with hemophilia</u> [as S.R of being affected is more considerable].

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