Answer:
<h3>The correct answers are :</h3>
<u>(B) They have nuclei </u>
<u>(C) They live in moist environments.</u>
Explanation:
Protists are very diverse group of organism, it contains all the organisms that does not fits into other kingdom. All of the protists are not heterotrophs some of them are autotrophs. They reproduce sexually but some of them reproduce asexually. Example: amoeba: binary fission. Some of the protists are multicellular. Some of them are unicellular too.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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as insects became exposed to pyrethroids, toxicity of pyrethroids weakened over time. which means that Most insects had the allele for pyrethroid resistance, but it remained masked. The allele for said pyrethroid resistance, evidently increased throughout the population.
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Answer:
Option (2).
Explanation:
Zygote is formed by the fusion of the male and female gamete during the process of sexual reproduction. The zygote undergoes further development inside the female womb.
The embryonic period starts from the third week after the conception. The important organs and structure development occur during the embryonic period. The formation of three germ layers occur in this period.
Thus, the correct answer is option (2)
Answer:
The oxygen atoms have electrons more often than hydrogen.
Explanation:
