Negative feedback mechanism occurs when the product or the output of a process inhibits the same process. When blood glucose level rises, body receptors stimulate beta cells in pancreas to release insulin. Insulin leads to uptake of glucose by cells, lowering the blood sugar levels. The lowered blood sugar level is again sensed by the receptors and they inhibit the secretion of insulin. Hence, insulin inhibits its own secretion by removing glucose from blood which makes it a negative feedback mechanism.
