Answer:
PFFT this might help? sorry if not mate
Explanation:
Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor suppressor genes. The p53 tumor suppressor protein plays a role in both the G1/S phase and G2/M phase checkpoints. The mechanism for this activity at the G1/S phase checkpoint is well understood, but its mechanism of action at the G2/M phase checkpoint remains to be elucidated. The p53 protein is thought to prevent chromosomal replication specifically during the cell cycle if DNA damage is present. In addition, p53 can induce a type of programmed cell death, or apoptosis, under certain circumstances. The general goal of p53 appears to be the prevention of cell propagation if mutations are present. The p53 protein acts as a transcription factor by binding to certain specific genes and regulating their expression. One of these, WAF1 or Cip1, is activated by p53 and is an essential downstream mediator of p53-dependent G1/S phase checkpoint control. The function of p53 can be suppressed by another gene, MDM2, which is overexpressed in certain tumorigenic mouse cells and binds to p53 protein, thus inhibiting its transcriptional activation function. Other cellular proteins have been found to bind to p53, but the significance of the associations is not completely understood in all cases. The large number of human cancers in which the p53 gene is altered makes this gene a good candidate for cancer screening approaches.
C eastern Europe
Mostly near the baltics and the Balkans, but Czech is also a slavic language.
Brain, Brain stem, Idk, Temporal Lobe....I think this is fairly for the most part correct
Its called pigment chlorophyll
To make an argument about how environmental imbalance affects the ecosystem of the Chesapeake Bay, research on reliable sources on the topic is necessary.
<h3 /><h3>How is the Chesapeake Bay?</h3>
The bay corresponds to the largest ecosystem of estuaries in the USA, being a source of diverse types of habitat for wildlife, with more than 3,600 species of animals and plants.
An example of the environmental imbalance in the area is the commercial and recreational fishing of blue crab, whose population had a significant reduction in 2022.
Therefore, environmental factors and human exploration are responsible for generating such an imbalance, and the development of policies and actions to promote sustainability is essential.
Find out more about sustainability here:
brainly.com/question/25713190
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