C) Florence was a center of trade with stable leadership under the Medici family.
Explanation:
Florence was one of the most politically, economically and culturally important cities in Europe from the 14th to 16th Century, and was also the cradle of the Italian Renaissance.
At the end of the Middle Ages, Florence financed the development of industry in almost all of Europe from Great Britain, Belgium, France, and all the way to Hungary.
Florence was the birthplace of Lorenzo Medici, a member of one of Italy's most important aristocratic families.
As many as two members of this family had the opportunity to become Pope in the 16th century.