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professor190 [17]
3 years ago
13

Galactosemia is a metabolic disorder characterized by the inability to metabolize the sugar galactose. People with galactosemia

suffer from liver, kidney, and brain damage among other symptoms. A gene mutation underlying galactosemia was identified by sequencing the genome of a person with galactosemia. What additional evidence would support the hypothesis that the mutation in the candidate gene causes the disease
Biology
1 answer:
Umnica [9.8K]3 years ago
7 0

Answer:

Genetic mapping for unequivocal identification of the potentially causative mutation  

Explanation:

Galactosemia is a genetic disorder caused by mutations in the Galactose-1-phosphate uridylyltransferase (GALT) gene, which encodes an enzyme involved in the metabolism of galactose. Gene mapping is a technique widely used in genetics to identify the position of one locus a chromosome by using molecular markers to estimate genetic distances. Genetic mapping provides useful evidence in order to identify when a disease that is transmitted from parent to offspring can be associated with one or more genes and then determine which gene/s is/are responsible for this condition.

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Human blood type is determined by multiple alleles (A, B, and O). Which ratio would result from a cross between a man with homoz
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Hallo~~

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In which way does the circulatory system rely on the skeletal ayatem?
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Duplication of chromosomes occurs during S phase of the cell cycle. Duplication requires the separation of complementary DNA str
frozen [14]

Answer:

Some statements of the question are missing but it can be understand as the Hydrogen bonds are Easy to break, Less amount of heat required, Less amount of enzyme needed and Can be broken by mild concentration of enzyme.

Explanation:

Weak bonds like hydrogen bonds are found to beneficial in some situations. During the duplication of chromosomes which occurs in S phase of cell cycle the DNA replicated. This replication is facilitated by separation of the two strands of DNA and formation of complimentary strand on the two primary strands. The enzymes involved in the process of separation of strands are DNA helicase and Topoisomerase mainly. As the bonds between the strands are weak hydrogen bonds, the enzymes function effectively without requiring extra heat or more saturation. It will found to be difficult if those bonds will be covalent bonds because they are much stronger than hydrogen bonds and are not easily broken by these enzymes. Extra processes will be required to break those strong bonds.

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3 years ago
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