Like histoplasmosis, coccidioidomycosis is acquired by the inhaling fungal spores.
<u>Arthrospores are formed by the hyphal fragmentation in this case. Once in body, fungus differentiates into the spherules which are filled with the endospores. </u>
Most of the C. immitis infections are self-limiting and asymptomati. The endospores are transported in blood, disseminating infection and thus leading to formation of granulomatous lesions on face and nose. I
<u>Thus, spherule is a thick-walled spherical structure which encloses the endospores and occurring in parasitic form of the fungi of genus Coccidioides.</u>
The common hepatic duct is formed by the union of the right and left hepatic ducts emerging out from the right lobe of the liver.
The right hepatic duct is responsible for draining bile from the right half of the body whereas the left hepatic duct drains it from the left side of the body.
At the junction of the right and left hepatic duct, the common hepatic duct gets formed which then joins the cystic duct and then the common bile duct is formed.