Griffith experimented and concluded that harmless bacteria could be transformed from one strain to another strain.
Further Explanation:
Frederick Griffith is a scientist who experimented with the mouse in 1928. He concluded that bacteria could acquire DNA by the process mainly referred to as transformation. In his experiment, he used two kinds of strain of <em>Streptococcus pneumoniae</em>. In this experiment, he infects mice with this bacterium.
Type-II R strain of bacterium is a rough strain and does not encapsulate with a layer of the polysaccharide. Another strain is Type-III S, which smooth strain and covered with the polysaccharide. This polysaccharide layer protects bacteria from immune cells present in the host. In this experiment, type-II S strain is injected in the mouse by the heat-killed method by which this strain has died. Type-II R is injecting normally and kills the mouse. Through this Griffith concluded that Type-II R strain is converted into lethal Type-III S strain by transforming principle.
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Answer Details:
Grade: High School
Subject: Biology
Topic: Transformation
Keywords: Transformation, mice, strain, streptococcus pneumonia, experiment, lethal, mouse, smooth strain, rough strain, transforming principle, normal, kill.