The answer is interconnected. You will come to find that everything that makes life possible on earth is all interconnected. It is just like the way all the human activities and necessities for the everyday life are all interconnected to nature.
Absorb? tell me if im wrong.
In physical science there are two types of "isolated systems"
1. Being a Physical System in which it is so far removed from other systems that it does not react with any of them.
2. Being a Thermodynamic System in which it is enclosed by rigid immovable walls of which neither mass nor energy can flow through.
I believe in this case although not stated that it would refer to a Thermodynamic System which would leave you with the only plausible answer as ENERGY AND MATTER CANNOT ENTER OR LEAVE.
None of the other answers make sense. Even if it were referring to Physical. Physical does not react with anything at all. An as you can see Thermodynamic does not allow for anything to pass through or leave.
Answer:
C. Mutations always cause a change in the in the way an organism looks.
Explanation: