Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Question: <em>The image below shows the life cycle of a plant. Which class does this plant belong to? </em>
<em>Answer: Gymnosperm</em>
<em>If you look up Gymnosperm Life Cycle of Google, and go to images, you will find a diagram/chart of the Gymnosperm Life Cycle, that matched the picture you gave.</em>
Hope this helps, have a good day. c;
Link to the picture of the diagram below...:
https://www.google.com/search?q=gymnosperm+life+cycle&rlz=1C1GCEB_enUS787US787&source=lnms&tbm=isch&sa=X&ved=0ahUKEwjR46qP1pDfAhUKR6wKHZVIBzQQ_AUIDigB&cshid=1544287366922000&biw=1707&bih=732&safe=active&ssui=on#imgrc=15Qy4QiBWX-1iM:
The limiting factors of an ecosystem are Habitat, Space, Resource abundance, or the reproductions<span />