Lesch Nyhan syndrome is characterized by behavioral and neurological abnormalities, and excess uric acid production in the body. It occurs in males, almost exclusively.
Changes (mutations) in the HPRT1 gene causes Lesch Nyhan syndrome and is inherited in a recessive X-linked way. Several symptoms of Lesch Nyhan syndrome are Inflammatory arthritis (gout), involuntary movements, self-injury and kidney stones.
1- Emigration and immigration rate 2- Death rate and birth rate These factors determine and affect the number of organisms of a species in a particular community. Hope this helps!