Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer: Sterilization.
Explanation:
Sterilization is the process that kills, or deactivates all forms of life so then a product is considered free of viable microorganisms. This process must be designed, validated and carried out to ensure that it is capable of eliminating the microbial load of the product.
Since sterility cannot be demonstrated without causing the complete destruction of the products, <u>sterility is considered when the probability of a product being contaminated is acceptably remote.</u> A critical product is considered sterile when the probability of a microorganism being present in an active or latent form is equal to or less than 1 in 1,000,000 (sterility safety factor 10^-6).
Agents that kill microorganisms are called microbicides or more commonly called "germicides". If the agent kills bacteria, it is called a bactericide. And if it kills fungi, then it is called a fungicide. It is important to consider than <u>after an exposure of the sterilized object to the air or its surroundings, it will have become contaminated again with microorganisms.</u>
Examples of sterilization include physical methods and chemical methods. Physical methods include:
- Wet heat (in steam autoclave)
- Dry heat (in sterilization oven)
- Radiation (gamma radiatio, electron beam, X-ray, ultraviolet, microwave, white light)
Chemical methods include a variety of chemicals in liquid and vapor form, for example:
- Hydrogen peroxide
- Chlorine dioxide
- Ozone gases
- Ethylene oxide
- Propylene oxide
- Peracetic acid
• Genes can contain more than one polyadenylation site, which alters the 3' of the mRNA transcript and the inclusion/exclusion of exons.
• mRNA transcripts from the same gene can be differentially spliced to include/exclude exons.
Answer:
Phosphate group is the structural difference between triglycerides and phospholipids. A triglyceride contains three fatty acids attached to the glycerol backbone whereas a phospholipid has two fatty acids and a phosphate group attached to the glycerol.
Explanation:
Answer: A) nucleotide
Explanation: I too, am also in biology :)
