Question

The 3' to 5' exonuclease activity associated with replicative DNA polymerases is responsible for increasing the accuracy of DNA synthesis approximately
a) 2 fold
b) 10 fold
c) 100 fold
d) 1,000
e) 1,000,000 fold

Answer 1

Answer:

The correct answer will be option-C.

Explanation:

DNA polymerase is an enzyme which replicates the DNA in 5' to 3' direction as well as it performs the exonuclease activity in  3' to 5'.

This exonuclease activity increases the rate of replication with high accuracy. This mechanism of proofreading is known as a proof-reading mechanism which increases the accuracy rate of DNA synthesis by 100- fold.

Thus, Option-C is the correct answer.