I guess it is called as Vulva
The answer is either all of the above or the third option
Most of these mutations change single amino acids in p53<span>. The altered protein cannot bind to DNA, </span>preventing<span> it from effectively regulating </span>cell<span> growth and division. As a result, DNA damage accumulates in </span>cells<span>, which can allow them to grow and divide in an uncontrolled way to form a cancerous tumor.</span>
Alcohol use. I know for a fact that that's the answer.