1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
ladessa [460]
2 years ago
14

A signaling pathway that stimulates cellular growth and division is positively regulated by a GTPase encoded by an autosomally l

ocated gene. During DNA replication in a cell within a large population of cells in culture, one of the two copies of this gene incurs a missense mutation that reduces the rate of hydrolysis of GTP to 1% of normal function.
Which of the following explanations best explains what effect this mutation might have on cells within this culture that are heterozygous for this mutation ?

Answers:

a.Because only one of the two copies of the GTPase encoding gene is affected, the cell will continue to grow and divide as normal.

b.Because the GTPase functions at a slower rate, signaling thought the pathway will occur with reduced efficiency and the cell's rate of growth and division will slow down.

c.Due to the reduced rate of hydrolysis of the GTP, signaling via the pathway will occur for a shorter period of time, so cells with the mutation will grow and divide more slowly.

d.Because the rate of hydrolysis is reduced, signaling will occur for a longer period of time and the cells will grow and divide more frequently.
Biology
1 answer:
Romashka-Z-Leto [24]2 years ago
8 0

Answer:

The correct answer is: a.

Explanation:

  • A Diploid organism possess two copies ( also called alleles) of each  autosomal gene, of which one copy of the gene is obtained from one of its parents and the other copy from its other parent.
  • During the process of replication, one of the alleles of the GTPase encoding gene undergoes a mis-sense mutation.
  • A Mis-sense mutation can be defined as a non-synonymous mutation in which one of the nucleotide in the sequence of the gene gets altered such that it causes a change in the amino acid encoded by the codon (triplet nucleotide message encoding for a single amino acid)  formed by the mutated nucleotide. A single amino acid change in the protein, if occurs in the functional site of the protein, can render a protein non-functional.
  • Hence, the mis-sense mutation in one of the alleles encoding for the GTPase gene causes the resulting protein produced from the mutated allele to have drastically reduced function (1%).
  • A heterozygous cell is one which has one copy of the normal allele and the other copy of the mutated allele of the GTPase encoding gene.
  • As one copy of the normal GTPase allele is present in such an individual, it can produce the normal GTPase protein that can assist in the process of cell growth and division.
  • Hence, the phenotype(expressed character) of  the heterozygous cell will not be affected due to the mutation and it will be able to grow and divide normally.
You might be interested in
Which statement is an example of mutualism?
sveta [45]
When 2 species bennift like fish cleaning a whale by eating off his skin
7 0
3 years ago
Read 2 more answers
Choose all the answers that apply.
Alekssandra [29.7K]
I thing the answer is a x-ray are cat scan hope this help
4 0
3 years ago
Read 2 more answers
When auditors wish to evaluate a sample statistically, an acceptable selection method is:
makvit [3.9K]
I would say A but i would get a second opinion
6 0
2 years ago
Why would mentioning a sensitive issue, such as divorce or infidelity, in a survey question influence how respondents answer lat
Paha777 [63]

Answer:

Sensitive questions will make the respondents cautious when answering the next question since they will still be thinking about it

Explanation:

The main aim of a survey is to collect or gather data that will increase knowledge in fields such as social research and Demography.

Thoughts, opinions and feelings are assessed.

To get credible data, the respondents have to be truthful and unbiased in answering the questions.

Therefore, asking sensitive questions will lead to the respondents being biased and less truthful on answering later questions.

3 0
3 years ago
Read 2 more answers
Which of the following about double stranded DNA is FALSE
Yuliya22 [10]

Answer:

To allow simultaneous replication of the leading and lagging strands by dimeric DNA pol III, the DNA of the leading strand has to be folded.

This is false.

Explanation:

I hope that helps. I don't know if it right or wrong, but good luck :)

8 0
3 years ago
Other questions:
  • Which of the following best describes a adaptation brought about by natural selection
    8·1 answer
  • PLS HELP SOMEONE PLS!!!! 99 POINTS!
    7·1 answer
  • What is meant by sex ​
    10·1 answer
  • __________ are a class of membrane proteins that increase a cell's permeability to certain ions.
    10·1 answer
  • Describe 1 way how people use hormones to improve plants they grow and use.
    12·1 answer
  • By when were robust australopithecines extinct?<br> a. 4 mya<br> b. 6 mya<br> c. 1 mya<br> d. 3 mya
    6·1 answer
  • Please help me please help me ​
    7·1 answer
  • 15. List the 4 major nutrient cycles
    14·2 answers
  • It was my first day in the class. I was very nervous as the college was away from my home town. I had to stay away from my paren
    7·1 answer
  • Please help me this is my last question.<br>You guys can do 1 sentence.<br><br>Thank you :)​
    14·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!