Answer:
PFFT this might help? sorry if not mate
Explanation:
Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor suppressor genes. The p53 tumor suppressor protein plays a role in both the G1/S phase and G2/M phase checkpoints. The mechanism for this activity at the G1/S phase checkpoint is well understood, but its mechanism of action at the G2/M phase checkpoint remains to be elucidated. The p53 protein is thought to prevent chromosomal replication specifically during the cell cycle if DNA damage is present. In addition, p53 can induce a type of programmed cell death, or apoptosis, under certain circumstances. The general goal of p53 appears to be the prevention of cell propagation if mutations are present. The p53 protein acts as a transcription factor by binding to certain specific genes and regulating their expression. One of these, WAF1 or Cip1, is activated by p53 and is an essential downstream mediator of p53-dependent G1/S phase checkpoint control. The function of p53 can be suppressed by another gene, MDM2, which is overexpressed in certain tumorigenic mouse cells and binds to p53 protein, thus inhibiting its transcriptional activation function. Other cellular proteins have been found to bind to p53, but the significance of the associations is not completely understood in all cases. The large number of human cancers in which the p53 gene is altered makes this gene a good candidate for cancer screening approaches.
Answer:
Because they have the same function to swim with, but have different structures and made of different material.
Explanation:
Answer:
The Sun, just like the Moon and the Earth, also has its own gravity which can affect the tides. Although the Sun is much larger than the Moon and has more gravity, it's also much further away, meaning its pull on the tides is less than half as strong as the Moon's. It still does have an effect, though.
So I think its B
Explanation:
It is the large intestine
Answer:
Mississippian fossils are abundant in portions of the Midwest and South and include vast beds of limestone and marble.
Explanation:
For example, the domed ceiling of the Jefferson Memorial in Washington, D.C., is made of Indiana limestone that was deposited during the Mississippian Period.By the end of the Carboniferous, reptiles had migrated well toward the interior of Pangea. These early pioneers went on to spawn the archosaurs, pelycosaurs, and therapsids of the ensuing Permian period. (It was the archosaurs that went on to spawn the first dinosaurs nearly a hundred million years later.)
