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USPshnik [31]
4 years ago
10

Particular receptor tyrosine kinases (RTKs) that promote excessive cell division are found at high levels on various cancer cell

s. A protein, Herceptin, has been found to bind to an RTK known as HER2. HER2 is sometimes excessive in cancer cells. This information can now be utilized in breast cancer treatment if which of the following is true?
Biology
1 answer:
Wittaler [7]4 years ago
7 0
<h2>HER2 is Cancer cells of breast caner</h2>

Explanation:

  • HER2 is a development advancing protein outwardly of all bosom cells.These malignancies will in general develop and spread quicker than other bosom diseases, yet are significantly more liable to react to treatment with drugs that focus on the HER2 protein.
  • It isn't clear in the event that one test is more precise than the other, however, FISH is increasingly costly and takes more time to get the outcomes.
  • In the event that the IHC result is 3+, the malignant growth is HER2-positive. This implies the HER2 status should be tried with FISH to explain the outcome.
  • Triple-negative bosom tumors have relatively little HER2 and furthermore don't have estrogen or progesterone receptors. Hormone treatment and medications that target HER2 are not useful in treating these malignant growths.
  • Hence, the answer of information of cancer treatment is "true"

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<u>Answer and Explanation</u>:

In reptiles, there are two mechanisms of sex determination:

-Genetic mechanisms, determined at the fertilization moment

-Environmental mechanisms, which are temperature-dependent.

Temperature is an environmental factor that affects different processes in organisms at a molecular level, biochemical level, or physiological level. In reptiles such as lizards, snakes, turtles, crocodiles, among other, temperature influences their embryonary development, their growth, daily activities, reproduction rate, sex determination, and etc.

In lizards, it occurs that whenever eggs are incubated at low temperatures, between 22 º and 27ºC, they produce a higher percentage of males, while eggs exposed to higher temperatures, 30ºC and above, produce more females. There are only a few degrees of temperature at which exposed eggs produce males and females equally.

The importance of knowing the mechanism of organisms´ sex determination lies in how climate change may be affecting wild populations due to fluctuations in temperature.

In the exposed example, the first cross between ZZ males and ZW females, genetics is the mechanism that determines the sex of progeny produced from eggs incubated at 24 and 35 degrees celsius. While in the second cross between ZZmales and ZZ females, temperature determines the sex of progeny produced from eggs incubated at 24 and 35 degrees celsius. This is, eggs exposed to temperatures below 28ºC will produce only males, so there won't be any female in the progeny. But eggs incubated at 30ºC and over will produce females, as shown in the table.

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Explanation:

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