I believe the answer is oxygen only
Water temperature influences the onset of fish spawn, aquatic vegetation growth and the biological demand for oxygen in ponds. Temperature increases it holds less oxygen. Also water stratification.
When cells communicate by the signaling process, one cell produces a signaling molecule that must be received by the signal receptor on or in the responding cell. Signaling molecules are often called ligands, a general term for molecules that bind specifically to other molecules (such as receptors).