There are many environmental negative direct outcomes of unused excess nitrogen from nitrogenous fertilizers. One of these is eutrophication. Eutrophication is the excessive richness of nutrients in a water body as a result of fertilizer run offs from the land, which causes a dense growth of plants in the water. Other negative outcomes are: green house effects, acid rain and contamination of underground water which has negative effects on human health.
Answer:
Cystic fibrosis mutation is recessive to normal allele because only one functional or normal allele is enough to produce a functional protein. So, if mutation is present in one allele then also, a normal protein can be made from normal allele. The presence of normal protein prevents the expression of disease.
In addition, mutated allele only results in the loss of function of protein which can be compensated by the expression of normal allele. It does not add any toxic effect to the protein. Consequently, the disease is inherited in autosomal recessive fashion.
In contrast, Huntington mutation not only alters the structure of the functional protein but also adds toxicity to it. The altered protein is enable to interact with 100s of other proteins and inhibit or decrease their function. So, if only one allele is present then also, the mutated protein will be produced and it will result in the phenotype. Consequently, it is inherited as autosomal dominant fashion.
The right answer is glutamate
Glutamate is a major excitatory neurotransmitter associated with learning and memory.
It is also associated with Alzheimer's disease whose first symptoms are felt in memory.
Most people unknowingly consume monosodium glutamate (MSG), a commonly used food additive.
An experiment was done on healthy patients, giving them 12 grams of glutamate. It was found that the experience led to headaches, nausea or jaw pain in 50-60% of cases.
It was also measured the level of glutamate contained in the muscles of patients with jaw problems. The tests concluded that the most painful muscles were those containing the highest levels of glutamate.
According to him, one of the keys to chronic pain could lie in the development of drugs that reduce the rate of glutamate.
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