Passive Transport: Simple Diffusion. Diffusion across a cell membrane is a type of passive transport, or transport across the cell membrane that does not require energy. ... Molecules that are hydrophobic, just like the hydrophobic region, can pass through the cell membrane by simple diffusion.
Answer:
Novobiocin target DNA GYRASE of gram positive bacteria.
Explanation:
Novobiocin is a bacteriostatic(slow down bacteria growth) or bactericidal i.e it kills bacteria , narrow spectrum antibiotics that target DNA GYRASE of gram positive bacteria. It acts by inhibiting the bacteria DNA gyrase hydrolysis thereby by interfering with the metabolic activities of bacteria. It is also a weak catalytic inhibitor of mammalian. Novobiocin inhibit DNA gyrase and topoIV by binding to the ATP pocket of GyrB and ParE, respectively.The Streptomyces strain that produces Novobiocin and it is more effective on gram positive bacteria that gram negative bacteria because gram negative bacteria are resistant to it.
D. Organisms specialized for living in a particular niche.
Through the process of transformation. Hope this helps.