In the beginning <span>of the RNA strand as a cap, a modified guanine nucleotide is added. After this, there is a removal of those segments of the RNA strand that do not actually code for the protein. And those RNA’s segments that do code for the protein are reconnected. And forking a tail, extra adenine nucleotides are added to the end of the RNA strand. The mRNA or messenger RNA which is already completed will then leave the nucleus. This whole process is called the RNA processing. Before the RNA copy of a protein encoding can be transported out of the nucleus and translated into protein, it must be first be modified in several ways. A precursor of mRNA, pre-mRNA is the primary transcription product of a gene. </span>
TOPOISOMERASE
There are various function of DNA toposisomerase such as:
1.accessing DNA- this happens during transcription and replication, DNA must be unwound for this to happen, Topoisomerase I make a single break to create an access.
2. Removing DNA super coils- Topoisomerase prevents DNA to be supercoiled, this happens during transcription of DNA to RNA
3. Strand breakage- It can introduce single strand breaks that are required for DNA to be exchanged to adjacent chromosomes.
Answer:
I believe the answer would be 'E. hotspots'.