<h2>CRISPR/Cas9</h2>
Explanation:
CRISPR can be used to reintroduce dystrophin back into the KO mouse
- CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats and is used to for gene editing
- CRISPR/Cas-mediated genome editing has been shown to permanently correct DMD mutations and restore dystrophin function in mouse models
- Germline editing by injecting zygotes with CRISPR/Cas9 editing component was first done in mdx mice by correcting the mutated exon 23
- Postnatal editing of mdx mice was then achieved using recombinant adeno-associated virus to deliver CRISPR/Cas9 genome editing components and correct the dystrophin gene by skipping or deleting the mutated exon 23 in vivo
- Germline and postnatal CRISPR/Cas9 editing approaches both successfully restored dystrophin function in the mice and same technique can be used for KO mouse model
Answer:
Heart disease is a non communicable disease because it does not happen due to any virus or bacteria.
Explanation:
Diseases caused due to virus and bacteria are mostly communicable. Heart Disease is caused due to poor supply of nutrients in hearts.
Answer:
Dampak negatif manusia terhadap lingkungan adalah:
Kelebihan penduduk, polusi, pembakaran bahan bakar fosil, dan penggundulan hutan. Perubahan seperti ini telah memicu perubahan iklim, erosi tanah, kualitas udara yang buruk, dan air yang tidak dapat diminum.
Dampak positif manusia terhadap lingkungan adalah:
Melindungi spesies yang terancam punah dan membersihkan danau dan laut memiliki efek positif terhadap lingkungan. Di rumah, Anda dapat membantu planet ini dengan mendaur ulang limbah dan menanam tanaman atau sayuran.
Answer:
The correct option is A. Steroid hormones exert their action by entering the nucleus of a cell and initiating or altering the expression of a gene.
Explanation:
Steroid hormones are derived from cholesterol and regulate multiple biological processes. All steroid hormones exert their action by crossing the plasma membrane and by binding with their respective intracellular receptors. They stimulate cell growth in a very different way, their lipophilic nature gives them the ability to cross lipid barriers, so, without the need for extracellular signals, these hormones can easily enter the cell, cross the cytoplasm and reach the nucleus. There they bind to specific receptors that are associated with DNA promoter regions, modifying their structure and promoting the expression of the genes under their control.
