Straightforward, dependable core facility HLA tissue typing service
Using state of the art genotyping technologies as used in HLA typing for organ transplantation
We work with genomic DNA, Saliva, Whole Blood, or Cryopreserved cells
Detailed results typically sent in 3 weeks
typeHLA Tissue Typing Service Overview
Typing technology options
New Next Generation Sequencing (NGS)
PCR-SSOP using Luminex®
(previously called Tier 1)
HLA Class I loci available
A, B and C
(whole Class I panel reported)
A, B, C
(can be ordered individually)
HLA Class II loci available
DRB1, DPB1 and DQB1
(whole Class II panel reported)
DRB1, DRB3,4,5, DPA1*, DPB1, DQA1*, DQB1
(can be ordered individually)
Resolution of typing data
Fully resolved 4 digit (allelic level) typing with no degeneracy for all samples
4 digit (allelic level) typing but with some degeneracy
Features / Restrictions
Only available for ordering whole Class I panel (3 loci) or whole Cass II panel (3 loci) or whole Class I and Class II panel (6 loci)
Can be ordered for each locus individually
Turnaround time (approximate)
3 weeks
Sample formats accepted
gDNA, Cryopreserved PBMCs/other Cells, Blood, Saliva
Report format
Electronic format (PDF, XLS) via secure webserver
Answer: <u>Option C; 48</u>
Explanation:
Let one number = x
Other number = x+2
According to question-
[x] [x+2] = 2400
+ 2x - 2400 = 0
Solving this equation, we get-
[x - 48] [x - 50 ] = 0
x = 48 or 50
Since 48 is the smaller number here, answer is option C
The major contribution made by Avery, MacLeod, and McCarty was 'transformation of nonvirulent cells with a DNA extract was blocked only if DNase was added'. This observation supported the idea that the transforming agent in Griffith's experiment was DNA.
The Avery–MacLeod–McCarty experiment showed that DNA was the transforming agent observed in Griffith's experiment.
Griffith's experiment (1928) suggested that bacteria were capable of transferring genetic information (DNA) by a process of horizontal gene transfer called transformation.
While the bacteria were killed by heat, Frederick Griffith observed that the DNA had was taken up by II-R strain bacteria via transformation.
Avery–MacLeod–McCarty experiment observed that protease enzymes did not destroy the transforming agent (but DNAse destroyed this transforming principle), thereby suggesting that the transforming agent in Griffith's experiment was bacterial DNA.
Learn more in:
brainly.com/question/927265?referrer=searchResults
Answer:
0.45 from mom and 0.05 from dad.
Explanation:
The recombinant progeny might occur due to the crossing over at the time of meiosis in which the exchange of chromosomes occur in the homologous chromosomes of non sister chromatids.
The progeny receives half of their chromosome from the mother and half from the father. The mother 50% AZ and 50% az chromosomes respectively. The 10% recombination has occured due to which the mother chromosomes is reduce upto 45%. The recombinant 10% will be aZ and Az and has 5% frequency. Mom has the ability of az chromosomes is 0.45 %. The father has the genotype 50% Az and 50% aZ. The 10% recombination has occured due to which the father chromosomes is reduce upto 45%. The recombinant will be az and AZ with 5% frequency. So, father has az with 0.05 % probability.
Thus, the answer is 0.45 from mom and 0.05 from dad.
