
Negative multiply negative = Positive
Negative multiply positive = negative

Thus the answer is -4a + 16b - 12c - 12d.
First you had to add by twenty-two from both sides of equation form.

Then simplify by equation.

Next, you divide by four from both sides of equation form.

Finally, simplify by equation.





Final answer: 
Hope this helps!
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-Charlie
Factoring may be the easiest one