A client is diagnosed with megaloblastic anemia caused by vitamin B12 deficiency. The health care provider begins the client on
cyanocobalamin (Betalin-12), 100 mcg I.M. daily. Which substance influences vitamin B12 absorption? A. Intrinsic factor
B. Hydrochloric acid
C. Histamine
D. Liver enzyme
The Vitamin B12 is used by the human body in the synthesis of the DNA, proteins and the hormones. The vitamin B12 is absorbed by the human body from the niacin, thiamine and folate.
The digestion of vitamin B12 is digested in the stomach by peptidases which breaks down the protein attached to the vitamin and then attaching the intrinsic factor to the vitamin B12. The vitamin B12 gets absorbed by the digestive in this form.
The intrinsic factor is a glycoprotein formed by the parietal cells present in the stomach which aids in the digestion of vitamin B12.
Vitamins are the chemical factors that are required in the diet in the small amounts. Vitamin B12 is the sub class of the vitamin B and its deficiency can cause megaloblastic anemia.
The parietal cells that are present in the stomach is responsible for the absorption of vitamin B 12 in the body. The vitamin then further binds with the intrinsuc chemicals and later absorbed in the ileum of the small intestine. Thus, vitamin B12 absorption depends on intrinsic factors.
