The value of n, the Hill coefficient, for hemoglobin is about 2 to 3 times as great as the value for myoglobin.
Hill Equation
The two closely related equations that help to explain the binding of macromolecules to ligands are called the Hill equation. It helps to quantify the interaction between various ligand binding sites.
Hill coefficient
It is used to describe the cooperativity of ligand binding. It can be positive and negative depending on the value of the Hill coefficient. If the value of the Hill coefficient is more than one then it exhibits positively cooperative binding and if it is less than one then it exhibits negatively cooperative binding. Then there is the noncooperative binding where the Hill coefficient value is one. As for the hemoglobin and myoglobin, the values are,
- Hill coefficient of hemoglobin is 2.7 - 3.
- Hill coefficient of myoglobin is 1.0.
Thus hemoglobin is positively cooperative and myoglobin exhibits noncooperative binding.
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D = m/V
m = 75g
V = 4 x 4 x 4 = 64 cm^3
d = 75/64 = 1 11/64 g/cm^3
Explanation:
charles darwin proposed thoery of natural selection.he had collected imnumerable specimens of plant and animals.he published concept survival of fittest. while explaining he says that There is always competition for food.only those organism survive which shows adptations in various reasons. it thoery of natural selection.
There are some objections,
1. natural selection is not only factor responsible for evolution.
2. darwin did not mention uesful and useless modifications.
3. There is no explanation about slow and abrupt changes
Answer:
62°F (17°C) to -60°F (-51°C) at the tropopause.
