The reason for the loss of color after the industrial revolution is that the light-colored moths were "selected against" by predators. These birds could only see the light ones against the newly dark, sooted background. Over time, these predators could no longer distinguish the dark ones from their natural dark, sooted background. Thus more light-colored moths stood out against the dark soot, and were eaten. And more dark-colored moths eluded the birds, survived to reproduce, passing on more of their dominant genes for dark color to their offspring. After several decades of hundreds of thousands of generations, most of the later generations were dark, due to selective advantage of camouflage to survive predation.
You would have to be very careful of cross-contamination. That means you would have to work very carefully and precisely with protective clothing, ensuring that none of your DNA (from skin or hair or even trace) gets into the sample you are working with
You would have to be very careful to check and record samples properly to ensure nothing got mixed up or mislabeled and this could be disastrous for criminal cases
All the material is very precious and sometimes only one sample exists, so you have to avoid making any mistakes. Experiments can't always be repeated.
