What changes in fatty acid metabolism would result from a mutation in the muscle carnitine acyltransferase I in which the mutant
protein has lost its affinity for malonyl-CoA but not its catalytic activity? A. Fatty acid synthesis in the mitochondria and fatty acid oxidation in the cytosol could occur simultaneously.
B. Fatty acid synthesis in the cytosol and fatty acid oxidation in the mitochondria could occur simultaneously.
C. Synthesis of malonyl carnitine could only occur at high malonyl-CoA concentration.
D. Synthesis of malonyl-CoA would no longer be inhibited carnitine.
<h2>B. Fatty acid synthesis in the cytosol and fatty acid oxidation in the mitochondria could occur simultaneously.</h2>
Explanation:
Carnitine acyltransferase I, is a mitochodrial enzyme also known as Carnitine palmitoyltransferase I (CPT1).
The acyl group is transferred to carnitine by the cytoplasmic form of the enzyme by Carnitine acyltransferase I
Malonyl coA would no longer inhibit fatty acid entry into the mitochondrion and beta oxidation, so there might be a futile cycle of simultaneous fatty acid synthesis in the cytosol and fatty acid breakdown in mitochondria.
I am pretty sure that the answer is equilibrium. I know it is a correct statement, but it may not be the statement you were looking for. Hope I helped :)
The food you've eaten goes down your oesophagus to your stomach, then to your small intestine, large intestine, and out out the anus during digestion, which can take anywhere from 24 to 72 hours.