Can be a number of things, rain fall quota, climate, population, vegetation..any of those.
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
Answer:
the answer is C
Explanation:
this shows how nutrients in the body because it enters the blood capillary which therefore goes through the small intestine.
I really hope this is helpful and understanding.
Explanation:
A frameshift mutation is an insertion or deletion in a sequence of DNA which disrupts the way the code is read. It occurs when the codons undergo a disruption through the deletion or insertion of one or multiple nucleotides (given that the number removed or added are not multiples of 3) - this alters the open reading frame; the amino acids produced through translation simply occur in a different sequence.
Further Explanation:
During the process of cell division, spontaneous changes within the genome can arise. These mutations are errors occur when copies of the DNA within the cell are made; mutations may range from small changes called single nucleotide polymorphisms, to large scale deletions, and additions which span multiple genes. There are two types:
- somatic: these only occur within certain cells, and arise from environmental factors such as UV light
- hereditary: occur within germ cells of the parent and later the fertilized egg which forms a zygote; these are present within all cells of the new organism.
Learn more about mutations at brainly.com/question/4602376
Learn more about DNA and RNA at brainly.com/question/2416343?source=aid8411316
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The 2 major components or parts that compose or make up the plasma membrane of a eukaryotic cell would be the phospholipids arranged as a bilayer, having phospholipids arranged side by side in an upright and inverted manner, allowing for the hydrophobic and hydrophilic regions to interact respectively, and also Protein molecules, more specifically Transmembrane Proteins and Integral Proteins.
