The best answer is B.
In the year 1962, Maurice Wilkins and Francis Crick jointly received the Nobel peace prize in physiology and medicine for their determination of the structure of deoxyribonucleic acid (DNA) in the year 1953. Their colleague called Rosalind Franklin was not there at the time because he had died of cancer earlier on.
Once the double helix structure and the molecules of DNA was known it brought a new and better understanding of heredity and hereditary disease
"Founder effect" is the one factor among the choices given in the question that is responsible for this phenomenon. The correct option among all the options that are given in the question is the second option or option "B". I hope that this is the answer that has actually come to your great help.
Changing the pH of the binding reaction mixtures can have a dramatic effect on ligand-protein binding. Altering the pH of the reactions between warfarin (which binds to site IIA of HSA via hydrophobic interaction) or ibuprofen (which binds to site IIIa of HSA via an ionic interaction) and HSA is likely to Affect warfarin-HSA binding but not ibuprofen-HSA binding.
