Two genes, BRCA1, located on chromosome 17q21 (5,6), and BRCA2, located on 13q12-13 (7–9), have been shown to predispose to familial breast cancer.
My guess:
I do not know the options to the blanks, but I'd say that the answer to the first one is "strongly linked". Think of a chromosome as a phylogenic chart → 2 species that are beside each other are strongly linked, if compared to 2 species 3 spots apart form each other. So, 2 genes that are close to each other are strongly linked.
I do not know the options to the blanks, but I'd say the answer to the second one is epistasis → which is the interaction between two different genes (different means they're not linked alleles).
Hope it helped,
BioTeacher101
<u>Answer</u>: Cystic fibrosis is a genetic disorder that causes thick mucus secretions.
<u>Explanation</u>:
- <em>Cystic fibrosis</em> is a genetic disorder caused by mutations in a gene that makes a protein called CFTR (cystic fibrosis transmembrane regulator).
- The CFTR protein normally functions as a channel for transport of chloride ions in cells responsible for mucus production.
- A person suffering from cystic fibrosis produces abnormal CFTR protein or no CFTR protein at all.
- This is the reason that thick, sticky mucus is produced instead of the thin, watery kind.
Proteins are the main structural and functional components of cells.
Each group of three bases in mRNA constitutes a codon, and each codon specifies a particular amino acid. The mRNA sequence is thus used as a template to assemble in order the chain of amino acids that form a protein.
The sequence of a protein is determined by the DNA of the gene that encodes the protein change in the gene's DNA sequence may lead to a change in the amino acid sequence of the protein. The sequence of amino acids of a protein determines protein shape, since the chemical properties of each amino acid are forces that give rise to intermolecular interactions to begin to create secondary structures, such as α-helices and β-strands.
To learn more about amino acid , here
brainly.com/question/14583479
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