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Complete Question:
A transmembrane receptor that functions at the cell membrane has an exoplasmic N-terminal sequence, a signal-anchor sequence, and a stop-transfer-anchor sequence. This protein was first inserted into the membrane where?
a) in the late endosome
b) in the Endoplasmic Reticulum
c) at the plasma membrane
d) in the cis- Golgi
Answer:
Option b) In the Endoplasmic Reticulum
Explanation:
A transmembrane receptor is a the amino acid chain of a transmembrane proteins.
The proteins is inserted into the Endoplasmic Reticulum through the process of translocation.
The amino acid chain of the transmembrane protein has an exoplasmic N-terminal sequence, a signal-anchor sequence which is hydrophobic alpha helix and a stop-transfer-anchor sequence which consists of a 22-25 hydrophobic amino acid sequence.
