You are working with a 125 million bp human chromosome (1 centimorgan = 1 million bp), and wish to use markers to map newgenes v

Question

SVETLANKA909090 [29]

3 years ago

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You are working with a 125 million bp human chromosome (1 centimorgan = 1 million bp), and wish to use markers to map newgenes v

ia linkage. In theory, what are the minimum number of markers/loci you need to map genes to this chromosome? Why?

Biology

1 answer:

Lena [83] · Answer 1 · 2022-03-18T13:32:53+03:00

Answer:

After every 0.192 centimorgan

Explanation:

If there are 125 million base pairs then according to the parallel ratio compare rule it should contain an average of 650 genes. If every gene has to be marked by a single marker on each end then a total number of 651 markers are used after every 0.192 centimorgan distance.