Question

Why are telomeres problematic for eukaryotic chromosome replication? a) They are highly repetitive and thus hard to replicate correctly. b) Telomerase is more error-prone than the normal DNA Polymerase. c) The T loop blocks formation of primers on the lagging strand. d) Removal of the lagging strand primer leaves a gap in the one of the strand's DNA sequences. e) Maintaining very long telomeres promotes cancer cell formation.

Answer 1

Answer: Option E

Maintaining very long telomeres promotes cancer cell formation.

Explanation:

Telomere refers to either of the sequences of DNA at each end of a eukaryotic chromosome.

Usually, in eukaryote chromosome replication, telomeres are not replicated.

Hence, they are usually lost resulting in the shortening of the telomere ends after repeated cycle of cell division. This also leads to cell aging and stoppage of cell division.

The shortening of telomere combined with stoppage of cell division, and cell aging initiation prevent CANCER, which thrives on lengthy telomeres