Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
Answer:
Plus end and kinesin.
Explanation:
Three important cytoskeleton components are microtubules, microfilaments and intermediate filaments. Microtubules are the polymer of tubulin and plays an important role in the movement of cell organelles and its structure.
Microtubules shows the process of polymerization and depolymerization at different ends. The plus end shows the polymerization and minus end shows the depolymerization process. The kinesin protein is required for the process of polymerization.
Thus, the correct answer is option (D).
Answer:
The given cell represents an animal cell, in which the organelle labelled as 'G' is mitochondrion. Mitochondria are membrane-bound organelles and their inner membrane is folded inward to form finger-like structures or cristae.
The mitochondria are known as the powerhouse of the cells as they are site for biochemical reactions of respiration and energy production.
Thus, the correct answer is 'mitochondrion.'
Everything that we eat and drink contains some percentage of water. So, to start, you have to know that the human body has receptors which estimate if we have enough water in our blood and cells in general. From these receptors, the information travels through the neurons to the part of the brain that is responsible for activation of different responses.
The digestive system is important because in its lower parts, liquids are absorbed and inserted in the bloodstream. Then through the bloodstream, they travel to all parts of the body and are absorbed by cells as needed. When blood passes through the body, it gets to the kidneys where water and electrolytes are filtered, reabsorbed if needed and excreted through the urine.
Now, if the brain has a signal that the body has a lack of liquids, it activates hormones which influence the bloodstream in both the digestive and the urinary system. In this case, the digestive system will absorb more liquids from food because the hormones will make the blood vessels in the digestive area larger, and on the other hand, we will produce less urine because the kidneys will get an assignment from the brain to filter liquids, but to reabsorb them again as much as possible.
