Question

You have identified a mutant mouse strain that is unable to properly clot its blood. you have determined that the mutation is not in any of the clotting factor proteins normally associated with hemophilia, but instead is due to another clotting factor being absent from the blood of the mutant mice. you were able to determine that the mutant gene differs by one amino acid compared to the wild-type. you synthesized the mutant protein in the lab, and discovered that, in contrast to the other mutant forms of hemophilic proteins, it has normal activity when tested in vitro. what is your hypothesis as to why this mutant protein results in hemophilia.

Answer 1

If a mouse is suffering from hemophilia that has other unknown factors, it might be due to silent or point mutations