<h2>KDEL Sequence & Protein Unfolding</h2>
Explanation:
(a) The distinction between proteins sent out from and those held in the ER has all the earmarks of being represented by two unmistakable sorts of focusing on successions that explicitly mark proteins as either bound for transport to the Golgi or bound for maintenance in the ER. Numerous proteins are held in the ER lumen because of the nearness of the focusing on grouping Lys-Asp-Glu-Leu (KDEL, in the single-letter code) at their carboxy end. In the event that this succession is erased from a protein that is regularly held in the ER (e.g., BiP), the transformed protein is rather moved to the Golgi and emitted from the cell. On the other hand, the expansion of the KDEL arrangement to the carboxy end of proteins that are typically discharged makes them be held in the ER. The maintenance of some trans membrane proteins in the ER is comparatively directed by short C-terminal successions that contain two lysine deposits (KKXX sequences)
(b) Proteins are large molecules composed of folded chains of amino acids. Every protein has a unique shape and that shape determines the things it does. You could think of them as keys that fit into certain locks around the body Proteins do lots of different things around the body, including speeding up biological processes, recognizing antibodies, providing structure to certain body parts, transporting substances, regulating genes, and responding to signals inside and outside the body Proteins range in size from small ones, such as insulin - only 51 amino acids long, to extremely large ones, such as titin almost 27,000 amino acids long. No matter their size, they must be folded into a particular shape in order to function. Sometimes, though, things go wrong and cause the protein to unfold
Answer:
Pituitary hormone replacement therapy
Explanation:
Hypopituitarism is a condition in which the pituitary gland is not producing one or more of its hormones or is producing them at lower than normal levels. Generally, these hormones stimulate other endocrine glands to produce their hormones. For example, if the pituitary gland doesn't make the thyroid-stimulating hormone (TSH), the thyroid gland doesn't work correctly.
The pituitary gland, which is located at the base of the brain, controls the production of hormones in all endocrine glands. In pituitary hormone replacement therapy, a patient takes hormones to replace the hormones not being produced by the pituitary gland. Such hormones include adrenocorticotropic hormone (ACTH), thyroid stimulating hormone (TSH), anti-diuretic hormone (ADH), sex hormones, prolactin, and growth hormone.
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This is a scientific question because you could conduct an experiment to test the theory.
Answer:
the answer is actually c
Explanation:
Cold air is more denser than hot air because ,when cold air of some density, say 'd' is heated, the molecules/atoms move apart from each other and so the volume expands. i hope that helped you
Answer:
Like bees and other pollinators, butterflies pick up pollen while they sip a flower's nectar. Once they're off to another plant, the pollen goes with them, helping to pollinate the plant species.
Explanation:
