Answer:
The correct answer will be
1. Glucose is converted to <u>glucose-6-phosphate</u>.
2. A <u>hexose kinase</u> is an enzyme.
3. Terminal phosphate of <u>ATP</u> to a substrate.
4. The product of this reaction is then to <u>form isomer</u> fructose-6-phosphate.
5. Fructose-6-phosphate is then phosphorylated by a second <u>phosphate ester synthesis</u> reaction,
6. giving <u>fructose-1,6 bisphosphate</u>.
Explanation:
Glycolysis is a sequential breakdown of glucose into product pyruvate releasing energy in the form of ATP and NADPH. This reaction takes place in ten steps in which the first three steps are ATP consuming reactions while last steps yield ATP molecules.
Step 1: includes the breakdown of glucose to glucose-6-phosphate in the presence of enzyme hexose kinase which helps in the transfer of phosphate group from ATP to intermediate formed. This reaction is known as Phosphate ester synthesis.
Step 2: includes isomerization of glucose-6-phosphate to fructose-6-phosphate which is again broken down to fructose-1,6-bisphosphate by phosphofructokinase which again transfers a phosphate group from ATP. This is also a Phosphate ester synthesis reaction.
Thus, filled options are the correct answer.