Prader-Willi syndrome (PWS) is a gentic disorder which has an impact on numerous physiological systems. PWS affected individuals (specifically babies) experience delayed growth, significant hypotonia (low muscle tone), and feeding issues. It does effect circadian rhythms in mice models.
SNORD116, often referred to as HBII-85, is a non-coding RNA (ncRNA) molecule that contributes to the alteration of other small nuclear RNAs (snRNAs). Unlike the majority of other snoRNAs, SNORD116 is not significantly complementary to ribosomal RNA and is expressed widely in the brain (but not in PWS patients).
According to the studies, SNORD116 cause sleep defect in patients with Prader-Willi syndrome. Same observation was seen in mouse models too. Paternal expression of SNORD116 is thought to be a potential gene for the sleep disruptions/circadian rhythm’s that the majority of PWS sufferers.
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The answer is D. 4 because its after perception
Terms matched with the right definitions.
1. An organism that can make its own food – Autotroph
2. A symbiotic relationship between two organisms in which one species benefits and no effect is apparent to the other species – Commensalism.
3. A cell that has a membrane-bound nucleus and/or organelles as its major characteristic -Eukaryote.
4. The study of organisms that are too small to be seen with the naked eye - Microbiology.
5. A disease-causing organism - A germ pathogen.
6. A one- or few-celled organism with chromosomes; may have characteristics of both animals and plants – Protist.
An autotroph is an organism that produces its own food from simple substances available in its environment. Autotrophs usually use inorganic chemical reactions or light energy in producing their food and are usually the producers in a food chain. Examples of autotrophs are plants and algae.
Commensalism is a type of relationship between organisms of two species where one organism benefits from the relationship and the other organism is not affected by it (neither benefits nor harmed).