the endocrine system and the nervous system are the two major regulating and communicating systems of the body. During rest and exercise, the nervous system along with endocrine system regulate the body mechanism to initiate the maintenance of Homeostasis in the body.
both endocrine and nervous system are both together involved in the transmission of chemicals signals which are important for physiological processes in the body . The difference is that endocrine system uses Hormones while nervous system uses neurotransmitters for chemical signalling.
The main area of the brain where these system work together and perform their function collectively is Hypothalamus where they signal each other when they receive proper stimulus.
