The lysine amino acid will provide a positive charge to the active site. If this mutation changed all of the lysine amino acids to aspartic acid, it will produce an enzyme having a negative charge.
<h3>Mutations and amino acids</h3>
A mutation is any alteration in the nucleotide (DNA) sequence of the genome of an organism.
A mutation that alters the active site of an enzyme will invariably affect its catalytic activity.
A mutation that involves a change in lysine (positive) to aspartic acid (negative) will produce a protein having a net negative charge.
Learn more about mutations here:
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