Answer:
The correct option is: <em>a deficiency of dopamine in the substantia nigra.</em>
Explanation:
The substantia nigra is the principal site involved in the physiopathology of Parkinson´s disease.
Cells from this area degenerate and die progressively causing important degeneration in the central nervous system. The cells that die -with no known reason- are those that produce dopamine and proportionate dopaminergic innervation to the encephalon. In fact, almost all the symptoms exhibited by patients with the disease can be explained by the lack of dopamine in the substantia nigra.
This area uses the neurotransmitter to communicate neurons from the base ganglia. Ganglia are responsible of modulating and modifying movements.
The nigrostriatal system participates in planning and automatic execution of learned movements. When the ganglia activity decreases, so it does the amount and velocity of movements, something typical of the disease.
ATP is a high-energy molecule found in every cell. Its job is to store and supply the cell with needed energy. hope this helps :)
The sensory receptors refer to the portions of the nervous system, which sense variations in the external or internal surroundings. The sensory input can be in various forms, comprising taste, pressure, light, sound, pH of blood, or levels of hormones, which are transformed into a signal and are transmitted to the brain or spinal cord.
In the sensory centers of the brain, the barrage of information is integrated and a response is produced. The response, that is, a motor output refers to a signal conducted towards organs via motor neurons, which then transforms the signal into some kind of action, like changes in heart rate, movement, discharge of hormones, and others.
In developed nations people have more fast food options which lead to cardiovascular disease. As well as screen time all day since this is one of the factors of cardiovascular disease. Undeveloped nations don't have fast-food or television to watch all day, since they play outside.
