Proteins are huge molecules that need to get an accurate tridimensional structure to accomplish their function.
In water, these molecules keep their hydrophilic parts in the outside and the hydrophobic part in the inside.
There are some treatments like changes in temperature or pH that provoke changes in the tridimensional structure of the protein. This process is known as DENATURATION. The protein losses its original native structure and its properties.
When denaturation occurs the protein tends to join together with other denaturalized proteins through the areas that repeal water, becoming coagulated.
Denaturation occurs when there is a disruption in the highly ordered or molecular structures, i.e, the secondary and tertiary structures ,present in the native state of the protein.
Denaturation can be caused through the application of some external stress, heat, inorganic salts among others.
